Osteoarthritis (OA) is by far the most common form of arthritis. It is strongly associated with ageing and is a major cause of pain and disability in older people. Osteoarthritis is characterised by focal loss of articular cartilage, subchondral osteosclerosis, osteophyte formation at the joint margin, and remodelling of joint contour with enlargement of affected joints.
Inflammation can occur but is not a prominent feature. Joint involvement in OA follows a characteristic distribution, mainly targeting the hips, knees, PIP and DIP joints of the hands neck and lumbar spine.
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