Hormonal Disorders

Weight loss

Weight loss may be physiological, due to dieting, exercise,starvation, or the decreased nutritional intake which accompanies old age. Weight loss of more than 3 kg over 6 months is significant and often indicates the presence of an underlying disease. Hospital and general practice weight records may be valuable in confirming that weight loss has occurred, as may reweighing patients at intervals; sometimes weight is regained or stabilises in those with no obvious cause.

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Obesity

Obesity is widely regarded as a pandemic, with potentially disastrous consequences for human health. Over one-quarter of adults in the UK were obese . There is increasing public awareness of the health implications of obesity. Many patients will seek medical help for their obesity, others will present with one of the complications of obesity, and increasing numbers are being identified during health screening examinations.

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Diabetes mellitus

Hyperglycaemia is a very common biochemical abnormality. It is frequently detected on routine biochemical analysis of asymptomatic patients, following routine dipstick testing of urine showing glycosuria, or during severe illness.

Occasionally, patients present as an emergency with acute metabolic decompensation. The key goals are to establish whether the patient has diabetes, and if so, what type of diabetes it is and how it should be treated.

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Thyroid Disorder

The most common presentations are

Hyperthyroidism

Hypothyroidism
enlargement of the thyroid (goitre or thyroid nodule).

Wide spread availability of thyroid function tests has led to the increasingly frequent identification of patients with abnormal results who are either asymptomatic or have non-specific complaints such as tiredness and weight gain.

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